Methyltestosterone is one of the oldest available oral steroids. It is quite androgenic, with minimal anabolic effects. For athletic purposes, methyltest is generally only used to stimulate aggression among power lifters and those looking to boost up their workouts. Methyltestosterone is an orally available form of the primary male androgen testosterone. Looking at the structure of this steroid, we see it is basically just testosterone with an added methyl group at the c-17 alpha position (a c-17 alpha alkylated substance). Alkylation such as this is necessary when administering testosterone (and other steroids) orally, as without it the liver will destroy most of the steroid during the “first pass”. The resultant compound “methylated-testosterone” was among the first functional oral steroids to be produced. This field of research has consequently improved greatly over the years, and today methyltestosterone is quite crude in comparison to many of the other orals that were subsequently developed.
Methyltestosterone offers little except androgenic side effects. It is quite toxic, elevating liver enzymes and causing acne, gynecomastia, aggression and water retention quite easily. Were one to tolerate these side-effects, Methyltestosterone will offer little more than some slight strength gains.
The action of this steroid is somewhat androgenic, with a moderate anabolic effect. As is typically seen with 17 alpha methylation, the resulting steroid has lower anabolic activity than its parent testosterone. Additionally it is extremely estrogenic, another property that seems to be enhanced when this alteration is present (when the steroid is receptive to the aromatase enzyme). The problem seems to be its conversion to the more biologically active estrogen 17-alpha methylestradiol. 17-alpha methylation in fact slows aromatization, however the potent nature of 1 -methylestradiol more than compensates for this. Additionally it has a very short half-life in the body, so the drug needs to be administered several times daily if a consistent blood level is to be obtained. All of this heightens the ratio of side effects to muscle growth enough to make methyltestosterone a very inefficient muscle-building drug. In order to administer an effective amount of hormone, the user simply must deal with too many estrogenic side effects, including water retention and gynecomastia, which can be very troublesome with this steroid. One may choose to addition an anti-estrogen such as Nolvadex and/or Proviron to combat related side effects, which should effectively minimize their intensity enough to make a cycle tolerable. The powerful antiaromatase Arimidex is a notably more effective option when dealing with aromatizable steroids, as it shows great ability to stop the conversion of androgens to estrogens.